MycoXpert is a mycoplasma removal reagent (or mycoplasma removal agent), a highly-efficient antibiotic that can be added to cell culture media. MycoXpert is active at low concentration for a broad range of contaminations with various mycoplasma subspecies. It acts by interference with the DNA replication machinery and thereby inhibiting Mycoplasma growth.
Mycoplasma is a genus of bacteria – the smallest bacteria cell yet to be discovered. Their main characteristic is that they lack a cell wall. Instead, the mycoplasma cell is enclosed by lipoproteins. This makes them resistant to, e.g., β-lactam antibiotics such as penicillin, which target the process of cell wall synthesis.
Mycoplasma, first discovered in 1898, was originally classified as a virus. There are more than 100 known species belonging to the genus Mycoplasma. They are free-living, self-replicating organisms, and when left untreated, can cause great harm to your cell cultures and research data, e.g., diminished cell growth and loss of cultures.
MycoXpert is provided as a 50x concentrate.
Appearance | Clear frozen liquid |
Storage and shelf life |
Store at ≤-15°C. Avoid repeated freeze-thaw cycles. Preparation of aliquots recommended. Once opened, store at +4°C and use within 4-6 weeks. |
Shipping conditions | Frozen (Dry ice) |
Thawing | Overnight at +2°C to +8°C. Swirl gently to homogenize. |
Working concentration | Recommended final concentration: 1x |
MycoXpert, Mycoplasma Removal Reagent (50x)
Cat. No. MYX-B (100 ml)